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Long term total parenteral nutrition through peripheral veins
International Surgery
|May 1, 1976
Summary
This study presents a novel total parenteral nutrition method omitting glucose, using Intralipid for calories. This approach avoids central venous catheters and shows no adverse effects in patients.
Area of Science:
- Clinical Nutrition
- Metabolic Support
- Intravenous Therapy
Background:
- Total parenteral nutrition (TPN) complications often stem from hypertonic glucose and central venous catheters.
- Alternative nutritional support strategies are needed to mitigate these risks.
Purpose of the Study:
- To describe a modified TPN regimen that omits hypertonic glucose.
- To evaluate the safety and efficacy of using Intralipid as the primary calorie source in TPN.
- To assess the feasibility of peripheral vein infusion for TPN.
Main Methods:
- A TPN system was developed excluding hypertonic glucose.
- Intralipid was utilized as the main caloric source.
- Protein hydrolysate and lipid solutions were administered simultaneously via peripheral veins.
Main Results:
- The modified TPN method was successfully implemented in 22 patients.
- Treatment durations ranged from three to 14 weeks.
- No deleterious effects were observed during the treatment periods.
Conclusions:
- Omitting hypertonic glucose and utilizing Intralipid via peripheral veins is a safe and effective TPN alternative.
- This method simplifies TPN administration and reduces risks associated with central venous access.
- Peripheral parenteral nutrition offers a viable option for caloric and protein delivery.