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De-esterification of cephalosporin para-nitrobenzyl esters by microbial enzymes
The Journal of Antibiotics
|February 1, 1976
Abstract:
Bacteria and actinomycetes were screened for esterase enzymes capable of removing the para-nitrobenzyl ester from cephalosporins. An esterase preparation from Bacillus subtilis was used to prepare cephalexin and 7-ADCA from the corresponding para-nitrobenzyl esters.
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