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[Congenital CMV meningoencephalitis treated with acyclovir]
1Pediatrics Dept., Hillel Yaffe Medical Center, Hadera.
Harefuah
|March 15, 1994
Summary
Cytomegalovirus (CMV) meningoencephalitis can affect infants, causing symptoms like irritability and convulsions. Early diagnosis using IgM anti-CMV antibodies and prompt treatment with acyclovir led to a full recovery in this case.
Area of Science:
- Pediatric Neurology
- Infectious Diseases
- Virology
Background:
- Cytomegalovirus (CMV) is a common virus that can cause serious illness in infants.
- CMV meningoencephalitis is a rare but severe neurological complication of CMV infection in newborns.
Observation:
- A 6-week-old infant presented with anorexia, irritability, and seizures.
- The infant had no significant past medical history or congenital anomalies.
- Seizures persisted despite initial hospitalization.
Findings:
- Diagnosis of CMV meningoencephalitis was confirmed by the presence of IgM anti-CMV antibodies.
- Cerebrospinal fluid analysis may be crucial for diagnosing CNS infections in infants.
Implications:
- Early detection and treatment of CMV meningoencephalitis are vital for favorable outcomes.
- Acyclovir is an effective antiviral agent for treating CMV infections in infants.
- This case highlights the importance of considering viral meningoencephalitis in the differential diagnosis of seizures in young infants.