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Hb Poitiers [alpha 45(CE3)His-->Asp]: a new hemoglobin variant with a two-fold increase in oxygen affinity
J Bardakdjian1, J Kister, H Wajcman
1INSERM U91, Hôpital Henri Mondor, Créteil, France.
Hemoglobin
|January 1, 1994
Abstract:
Hb Poitiers or alpha 45(CE3)His-->Asp was found in a 9-year-old French Caucasian boy. The structural modification concerns a heme contact and is responsible for an increased oxygen affinity and a faster than normal rate of autooxidation.