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[Gastroesophageal reflux and bronchial asthma: pH-metric patterns in non allergic children]

M Cinquetti1, L A Boer, G Cracco

  • 1Divisione di Pediatria dell'Ospedale Maggiore, Verona, Italia.

La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics
|November 1, 1993
PubMed

Insights

Gastroesophageal reflux (GER) in children with asthma was studied using pH monitoring. The total number of reflux events over 24 hours may help identify asthma in children without allergies.

Area of Science:

  • Pediatric Pulmonology
  • Gastroenterology
  • Allergy and Immunology

Background:

  • Gastroesophageal reflux (GER) is a potential factor in pediatric asthma.
  • Understanding GER patterns in asthmatic children without allergies is crucial for diagnosis.

Purpose of the Study:

  • To investigate the characteristics of GER in asthmatic children without allergies using 24-hour intraesophageal pH monitoring.
  • To identify specific pH monitoring parameters that can differentiate asthmatic children from healthy controls.

Main Methods:

  • Computerized 24-hour intraesophageal pH monitoring was performed on 27 asthmatic children without allergies and 10 healthy controls.
  • Asthmatic children were categorized into three groups based on Reflux Index (R.I.) and positional GER patterns.
  • Data analysis focused on the total number of refluxes and their distribution in relation to posture.

Main Results:

  • Group A, characterized by a higher R.I. and more GER in the standing position, was the most frequent among asthmatic children.
  • No significant difference in the total number of refluxes was found between asthmatic groups (A, B, C).
  • A significant prevalence of the total number of refluxes was observed in Group C compared to the control group (D).

Conclusions:

  • The total number of refluxes detected by 24-hour pH monitoring appears to be a significant parameter for characterizing children with bronchial asthma and without allergies.
  • Positional GER patterns may further refine the understanding of GER in pediatric asthma.
  • This study suggests pH monitoring can aid in identifying GER-related asthma in non-allergic children.

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