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Complete heart block and torsade de pointes associated with thioridazine poisoning
D T Hulisz1, S L Dasa, L D Black
1Akron General Medical Center, Department of Medicine, OH 44307.
Pharmacotherapy
|March 1, 1994
Abstract:
A 72-year-old woman attempted suicide with thioridazine 3000 mg and 60 tablets of acetaminophen 325 mg plus codeine 30 mg. She was semicomatose and had persistent third-degree atrioventricular block, progressive hypotension, and an episode of torsade de pointes. Heart block, arrhythmias, and hypotension resolved within 48 hours, and the patient recovered without adverse sequelae.