Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Toxic lung damage caused by mitomycin C]

G Lenci1, J Müller-Quernheim, J Lorenz

  • 1Abteilung für Pneumologie, Johannes Gutenberg-Universität, Mainz.

Pneumologie (Stuttgart, Germany)
|March 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Performance of the ATLAS trigger system in 2015.

The European physical journal. C, Particles and fields·2017
Same author

Reconstruction of primary vertices at the ATLAS experiment in Run 1 proton-proton collisions at the LHC.

The European physical journal. C, Particles and fields·2017
Same author

Jet reconstruction and performance using particle flow with the ATLAS Detector.

The European physical journal. C, Particles and fields·2017
Same author

Measurements of electroweak [Formula: see text] production and constraints on anomalous gauge couplings with the ATLAS detector.

The European physical journal. C, Particles and fields·2017
Same author

Topological cell clustering in the ATLAS calorimeters and its performance in LHC Run 1.

The European physical journal. C, Particles and fields·2017
Same author

[Criteria for treating MRSA in sputum].

Der Internist·2017

Mitomycin C (MMC) can cause rare lung toxicity. This case report details a pulmonary reaction after MMC monotherapy, confirmed by bronchoalveolar lavage and lung biopsy.

Area of Science:

  • Oncology
  • Pulmonology
  • Toxicology

Background:

  • Mitomycin C (MMC) is an effective antineoplastic agent used in cancer treatment.
  • Lung toxicity is a rare but serious side effect associated with MMC therapy.
  • Pulmonary damage following MMC monotherapy is infrequently reported in medical literature.

Observation:

  • This report details a specific case of a patient experiencing a pulmonary reaction after receiving MMC as a single agent.
  • Diagnostic procedures included bronchoalveolar lavage (BAL) and a transbronchial lung biopsy.
  • Radiological imaging, including CT scans and high-resolution CT (HR-CT), were utilized to assess the lung condition.

Findings:

  • Bronchoalveolar lavage (BAL) results indicated lymphocyte alveolitis.

Related Experiment Videos

  • The T lymphocytes in BAL showed a normal CD4/CD8 ratio.
  • Histopathological examination of the lung biopsy revealed a florid alveolitis.

    • Implications:

    • This case highlights the importance of recognizing and investigating pulmonary reactions in patients treated with Mitomycin C.
    • Understanding the diagnostic findings (BAL, biopsy, imaging) can aid in early detection of MMC-induced lung injury.
    • Further research into the mechanisms and management of Mitomycin C-related pulmonary toxicity is warranted.