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Molecular biology of breast carcinoma
1Department of Biochemistry and Molecular Biology, Lombardi Cancer Research Center, Georgetown University Medical Center, Washington, D.C. 20007.
World Journal of Surgery
|January 1, 1994
Abstract:
During the last several years basic research has resulted in the identification of many of the factors involved in signal transduction pathways, leading us to a greater understanding of the mechanisms of growth control in breast cancer cells. Many of these factors are the products of proto-oncogenes or suppressor genes. This review describes the role of some of these factors in breast cancer development, progression, and metastasis and discusses implications for future directions.