Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Report of the Biodegradable Implants Study Group]

K E Rehm1, H J Helling, L Claes

  • 1Klinik für Unfall-, Hand- und Wiederherstellungschirurgie, Universität zu Köln.

Aktuelle Traumatologie
|April 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Study of the ^{22}Mg Waiting Point Relevant for X-Ray Burst Nucleosynthesis via the ^{22}Mg(α,p)^{25}Al Reaction.

Physical review letters·2023
Same author

Retraction.

Science (New York, N.Y.)·2023
Same author

Subtyping youngsters with obesity: A theory-based cluster analysis.

Appetite·2021
Same author

The drive for thinness: Towards a mechanistic understanding of avoidance behaviors in a non-clinical population.

Behaviour research and therapy·2021
Same author

Obstetrical outcome after B-Lynch sutures and ligation of uterine arteries: A case report.

Case reports in women's health·2021
Same author

Predicting the incidence of non-suicidal self-injury in college students.

European psychiatry : the journal of the Association of European Psychiatrists·2019
Same journal

[Injury of the popliteal artery as a complication of knee dislocation].

Aktuelle Traumatologie·1994
Same journal

[Laryngeal insufficiency as a post-traumatic complication of facial skull injury].

Aktuelle Traumatologie·1994
Same journal

[Arthrofibrosis after replacement-plasty of the anterior cruciate ligament--incidence, causes, therapy].

Aktuelle Traumatologie·1994
Same journal

[Delayed management of rupture of the Achilles tendon. Long-term follow-up in comparison with early operation].

Aktuelle Traumatologie·1994
Same journal

[Indications for surgical treatment of clavicular fractures].

Aktuelle Traumatologie·1994
Same journal

[Variability of the length and joint angle proportions of the distal radius].

Aktuelle Traumatologie·1994
See all related articles

Biodegradable polylactide pins (Polypin) demonstrate durability and safety for osteochondral lesion fixation. Clinical studies show good results with no infections, marking a significant advancement in orthopedic implants.

Area of Science:

  • Orthopedic surgery
  • Biomaterials science
  • Polymer chemistry

Background:

  • Development of biodegradable implants is crucial for reducing long-term complications.
  • The German Section of AO/ASIF-International established a group for biodegradable implant research.
  • Polylactide materials are promising candidates for biodegradable orthopedic devices.

Purpose of the Study:

  • To evaluate the efficacy and safety of a novel biodegradable implant for osteochondral lesions.
  • To assess the in-vitro and in-vivo performance of L/DL-polylactide 70/30.
  • To report clinical outcomes of biodegradable pins in orthopedic fixation.

Main Methods:

  • In-vitro screening of various polylactide materials and copolymers.
  • Animal experiments to assess implant durability and degradation.

Related Experiment Videos

  • Clinical application of biodegradable pins (Polypin) with radiopaque markers for osteochondral lesion fixation.
  • Multicenter clinical study involving 57 patients.

    • Main Results:

    • L/DL-polylactide 70/30 was selected based on in-vitro screening.
    • Animal studies confirmed long durability (9 months) and subsequent degradation.
    • Clinical experience exceeding three years showed good results and no infections.
    • Polypin represents the first biodegradable implant from the AO/ASIF group.

    Conclusions:

    • Biodegradable polylactide pins (Polypin) are effective and safe for treating osteochondral lesions.
    • The material demonstrates suitable durability and degradation profiles for orthopedic applications.
    • Polypin offers a promising alternative to traditional fixation methods, with a favorable clinical safety profile.