Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Risk factors for herpes simplex-induced keratitis: a case-control study

B M Brandt1, J Mandleblatt, P A Asbell

  • 1Department of Community Medicine, Mount Sinai School of Medicine, New York.

Annals of Ophthalmology
|January 1, 1994
PubMed
Summary

This study found no link between herpes simplex-induced keratitis (HSK) and common risk factors like allergies or steroid use. Further research is needed to understand the epidemiology of this eye infection.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

sPLA<sub>2</sub>-IIa participates in ocular surface inflammation in humans with dry eye disease.

Experimental eye research·2020
Same author

Conductive keratoplasty for the correction of hyperopia.

Transactions of the American Ophthalmological Society·2002
Same author

Long-term follow-up of corneal graft survival following bone marrow transplantation in the Maroteaux-Lamy syndrome.

The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc·2001
Same author

Optical coherence tomography of Intacs.

Journal of cataract and refractive surgery·2001
Same author

Long-term follow-up of Intacs from a single center.

Journal of cataract and refractive surgery·2001
Same author

Two-year outcomes of intrastromal corneal ring segments for the correction of myopia.

Ophthalmology·2001

Area of Science:

  • Ophthalmology
  • Virology
  • Epidemiology

Background:

  • Herpes simplex virus (HSV) is a common cause of infectious keratitis.
  • Several risk factors have been postulated for herpes simplex-induced keratitis (HSK), but their prevalence remains unclear.
  • Understanding HSK epidemiology is crucial for effective prevention and treatment strategies.

Purpose of the Study:

  • To investigate the prevalence of previously postulated risk factors for herpes simplex-induced keratitis (HSK).
  • To compare risk factor prevalence in HSK patients versus control subjects.
  • To identify potential associations between HSK and factors such as sex, atopy, and medication use.

Main Methods:

  • A case-control study comparing 42 HSK patients with control subjects across three institutions.

Related Experiment Videos

  • Data collection focused on patient demographics, medical history, and exposure to potential risk factors.
  • Statistical analysis was employed to determine associations between HSK and various factors.

    • Main Results:

    • The average age of HSK patients was 46.3 years, with the first episode occurring around 41.7 years.
    • Recurrent HSK affected 75% of patients, and bilateral infections occurred in 11.76%.
    • No statistically significant associations were found between HSK and male sex, atopy, corticosteroid use, intraocular trauma, contact lens wear, or herpes labialis.

    Conclusions:

    • This pilot study did not identify significant associations between HSK and commonly suspected risk factors.
    • The findings suggest that current hypotheses regarding HSK epidemiology may require re-evaluation.
    • Further, larger-scale investigations are warranted to clarify the etiological factors and epidemiology of HSK.