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Choroidal malignant melanoma

S F Murphy1, C F Mahl, S M Bloom

  • 1Retina Associates, Louisville, Kentucky.

Optometry Clinics : the Official Publication of the Prentice Society
|January 1, 1993
PubMed
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Choroidal nevi, often benign, may precede malignant melanomas. Diagnosis involves multiple methods, with treatment varying by tumor size, from observation to enucleation.

Area of Science:

  • Ophthalmology
  • Oncology

Background:

  • Choroidal nevi are common, found in 1-2% of patients during routine eye exams.
  • These benign lesions are considered potential precursors to choroidal malignant melanomas.

Purpose of the Study:

  • To outline the diagnostic and treatment approaches for choroidal malignant melanoma.

Main Methods:

  • Diagnosis is multifactorial, utilizing funduscopic, angiographic, and ultrasonographic findings.
  • A metastatic workup is initiated upon melanoma diagnosis.
  • Treatment strategies are size-dependent: observation for small tumors, radiation or enucleation for medium, and enucleation for large tumors.

Main Results:

  • Choroidal malignant melanoma incidence is approximately 6 cases per million persons annually in the US.

Related Experiment Videos

  • Treatment modalities include observation, radioactive plaque therapy, external beam radiation, and enucleation.
  • Conclusions:

    • Management of choroidal melanoma is tailored to tumor size.
    • Ongoing research aims to determine the optimal treatment strategy.