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Updated: Jul 24, 2026
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Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Successful pregnancy in I.D.D.M. with intravenous programmable insulin pump
1Department of Endocrinology, Beaumont Hospital, Dublin, Ireland.
Irish Journal of Medical Science
|February 1, 1994
Summary
This case report details a novel complication of insulin pump therapy in a pregnant patient with insulin resistance: clot formation at the catheter tip. Anticoagulant therapy successfully resolved this issue.
Area of Science:
- Endocrinology
- Obstetrics
- Pharmacology
Background:
- Subcutaneous insulin resistance presents management challenges, often requiring intravenous insulin via infusion pumps.
- Pregnancy exacerbates insulin resistance, necessitating careful glycemic control.
- Previous studies focused on intraperitoneal insulin administration during pregnancy.
Observation:
- A 31-year-old primigravida with subcutaneous insulin resistance experienced an unusual complication during insulin pump therapy.
- Clot formation at the catheter tip was identified as a novel clinical issue.
Findings:
- The patient's clot formation at the insulin pump catheter tip was successfully treated with anticoagulant therapy.
- This represents a previously undescribed complication of intravenous insulin infusion in pregnancy.
Implications:
- Highlights the potential risk of catheter-tip thrombosis with insulin pump use in pregnant patients.
- Suggests anticoagulant therapy as a viable treatment for this complication.
- Informs clinical practice regarding monitoring and management of insulin pump therapy in high-risk pregnancies.
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