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Hemodynamic changes in acute adrenal insufficiency

G Bouachour1, P Tirot, N Varache

  • 1Service de Réanimation Médicale, Centre Hospitalier Universitaire, Angers, France.

Intensive Care Medicine
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

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Acute adrenal insufficiency can cause shock, presenting as either myocardial depression or hyperdynamic shock. Glucocorticoid treatment improved cardiac function in patients with adrenal insufficiency.

Area of Science:

  • Cardiology
  • Endocrinology
  • Intensive Care Medicine

Background:

  • Acute adrenocortical insufficiency is an uncommon cause of shock.
  • Hemodynamic instability can be the primary presentation.

Purpose of the Study:

  • To describe the cardiovascular changes in patients with acute adrenal insufficiency and hemodynamic instability.

Main Methods:

  • Retrospective and prospective study design.
  • Involved 6 patients in a university hospital's medical intensive care unit.
  • Utilized right cardiac catheterization for hemodynamic assessment.

Main Results:

  • Two hemodynamic states observed: myocardial depression with hypovolemia (3 patients) or hyperdynamic shock (3 patients).

Related Experiment Videos

  • Intravenous fluid therapy could convert low cardiac output states to hyperdynamic shock.
  • Glucocorticoid treatment improved left ventricular systolic work index in 4 patients.
  • Conclusions:

    • Consider acute adrenocortical insufficiency in shock cases resembling septic shock without a clear infectious source, especially after significant fluid resuscitation.