Related Experiment Videos
Coring: a potential problem in eye surgery
Journal of Cataract and Refractive Surgery
|March 1, 1994
Summary
Needle injections can transfer rubber particles from vial stoppers into the eye and surrounding tissues. Microscopic rubber fragments were detected in all tested syringe aspirates, posing a potential risk during medical procedures.
Area of Science:
- Ophthalmology
- Materials Science
Background:
- Needle insertion through rubber septa is common in medical practice.
- Potential for particulate contamination exists during drug preparation.
Purpose of the Study:
- To investigate rubber particle aspiration from vial stoppers.
- To assess the presence of these particles in injectable solutions.
Main Methods:
- Syringes were used to aspirate contents from rubber-stoppered vials.
- Aspirated samples were centrifuged and analyzed microscopically for particulate matter.
Main Results:
- Microscopic rubber particles were found in all tested aspirates.
- Contamination was present even in partially used medication vials.
Conclusions:
- Needle use with rubber stoppers can lead to particulate contamination.
- This contamination poses a potential risk for ocular and periocular injections.