Related Experiment Video
Updated: Aug 1, 2026
A Novel Technique of Rescuing Capsulorhexis Radial Tear-out using a Cystotome
Published on: January 17, 2011
Coring: a potential problem in eye surgery
Abstract:
Any needle passing through a rubber stopper can aspirate a core of rubber. This rubber may then be injected into the eye or into the retrobulbar or peribulbar space. Aspirates from a number of syringes were spun down in a centrifuge and examined for microscopic particles. All specimens contained microscopic particles even from half-used bottles of Xylocaine.
Insights
Needle injections can transfer rubber particles from vial stoppers into the eye and surrounding tissues. Microscopic rubber fragments were detected in all tested syringe aspirates, posing a potential risk during medical procedures.
Area of Science:
- Ophthalmology
- Materials Science
Background:
- Needle insertion through rubber septa is common in medical practice.
- Potential for particulate contamination exists during drug preparation.
Purpose of the Study:
- To investigate rubber particle aspiration from vial stoppers.
- To assess the presence of these particles in injectable solutions.
Main Methods:
- Syringes were used to aspirate contents from rubber-stoppered vials.
- Aspirated samples were centrifuged and analyzed microscopically for particulate matter.
Main Results:
- Microscopic rubber particles were found in all tested aspirates.
- Contamination was present even in partially used medication vials.
Conclusions:
- Needle use with rubber stoppers can lead to particulate contamination.
- This contamination poses a potential risk for ocular and periocular injections.
Related Concept Videos
01:25Glaucoma: Overview
01:28Angle Closure Glaucoma: Treatment