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Related Experiment Videos

Massive upper gastrointestinal bleeding due to Candida esophagitis

A Kumar1

  • 1Section of Critical Care Medicine, University of Manitoba, Canada.

Southern Medical Journal
|June 1, 1994
PubMed
Summary

Hemorrhagic candidal esophagitis causing severe upper gastrointestinal bleeding is rare, especially without bleeding risks. Intravenous amphotericin successfully treated a patient with renal failure, despite initial therapy failure.

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Nephrology

Background:

  • Esophageal candidiasis typically presents with dysphagia and odynophagia.
  • Hemorrhage from esophageal candidiasis is uncommon, particularly in patients without bleeding diathesis.

Observation:

  • A case of recurrent, severe upper gastrointestinal bleeding was observed.
  • The patient had end-stage renal disease and presented with bleeding, not typical esophageal symptoms.
  • Oral thrush was present only initially.

Findings:

  • Standard treatment with blood products was ineffective for the massive bleeding.
  • Intravenous amphotericin administration led to the resolution of hemorrhagic candidal esophagitis.

Implications:

Related Experiment Videos

  • This case highlights a rare but severe presentation of esophageal candidiasis.
  • It underscores the importance of considering fungal infections in unexplained gastrointestinal bleeding, even without typical symptoms.
  • Effective treatment with intravenous amphotericin was demonstrated in a complex patient population.