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A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice
Published on: April 13, 2010
[The fiber bronchoscopic evaluation of the bronchial inflammatory changes and hyperreactivity in bronchial asthma
Abstract:
Bronchofibroscopic bronchial examination detected inflammation-induced changes in the bronchi in the form of mucosal thickening (edema), small masses of the sputum and occasional hyperemia in the majority of the examinees with bronchial asthma. In combination with bronchoalveolar lavage, bronchofibroscopy provides diagnosis of bronchial hyperreactivity basing on determination of segmentary bronchial stenosis in response to salt solution instillation. The degree of this stenosis can evidence the degree of hyperreactivity of the bronchi. Bronchofibroscopic signs of bronchial hyperreactivity appear more distinctly in asthma aggravations, in severe run of the disease, in pronounced inflammation.
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