[The etiology and pathogenesis of penile oleogranulomas]

The paper reports the experience with surgical treatment of 25 males with penile paraffinomas. A detailed pathomorphological examination of the removed tissues allowed the authors to propose an original idea on the process dynamics upon subcutaneous administration of oily substances. A pathogenetic relationship was established between various stages of chronic inflammation in paraffinoma up to development of rapidly progressing fibrous process the malignancy of which increases in joining infection. The authors advocate early operative interventions instead of long-term conservative therapy in penile paraffinomas complicated by infection.