Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Malignant anal tumours

G T Deans1, J J McAleer, R A Spence

  • 1Department of Surgery, Belfast City Hospital, Queen's University of Belfast, UK.

The British Journal of Surgery
|April 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Local Control: Also a Strength of Radiotherapy Training?

Clinical oncology (Royal College of Radiologists (Great Britain))·2021
Same author

A Qualitative Assessment of Radiotherapy Training at a UK Regional Cancer Centre.

Clinical oncology (Royal College of Radiologists (Great Britain))·2020
Same author

Radiation Oncology: A Clinical Update from The North West Cancer Centre.

The Ulster medical journal·2019
Same author

The role of the final FRCR examination in specialist training in clinical oncology.

Clinical oncology (Royal College of Radiologists (Great Britain))·2011
Same author

Elevated serum beta-hCG due to a tumour of unknown origin.

The Ulster medical journal·2004
Same author

Radiation recall dermatitis in a patient treated with dacarbazine.

Clinical oncology (Royal College of Radiologists (Great Britain))·2002
Same journal

Making the OR work: a socio-material study of ergonomics in the operating room.

The British journal of surgery·2026
Same journal

A randomized, noninferiority clinical trial of Single-Shot Intrathecal Morphine versus Continuous Wound Infiltration for postoperative pain control after open pancreatoduodenectomy.

The British journal of surgery·2026
Same journal

Trimester-Specific Safety of Laparoscopic versus Open Abdominal Surgery During Pregnancy: A Systematic Review and Meta-analysis.

The British journal of surgery·2026
Same journal

The Gut Microbiome in Surgical Oncology: Mechanisms, Perioperative Outcomes, and Therapeutic Opportunities.

The British journal of surgery·2026
Same journal

Patient-led, home-based follow-up for colorectal cancer: the DISTANCE multicentre stepped-wedge cluster-randomised trial.

The British journal of surgery·2026
Same journal

Correction to: Reduced secretory efficiency in parathyroid carcinoma: diagnostic value of the PTH-to-tumour-volume ratio.

The British journal of surgery·2026
See all related articles

Anal tumors, including squamous cell carcinoma, are linked to smoking and HPV. Radiotherapy with chemotherapy is preferred for anal canal tumors, while local excision is suitable for anal margin tumors.

Area of Science:

  • Oncology
  • Gastroenterology
  • Epidemiology

Background:

  • Anal tumors constitute 5% of anorectal cancers, with distinct entities in the anal canal and anal margin.
  • Key etiological factors include smoking and sexual behaviors, particularly homosexual anal intercourse, linked to human papillomavirus (HPV) infection.

Purpose of the Study:

  • To review the epidemiology, histology, and treatment strategies for anal tumors.
  • To differentiate management approaches for anal canal versus anal margin tumors.

Main Methods:

  • Literature review and synthesis of current evidence on anal tumor diagnosis and treatment.
  • Analysis of treatment outcomes, including response rates, survival, and functional outcomes.

Main Results:

Related Experiment Videos

  • Squamous cell carcinoma is the predominant histological type (95%), with adenocarcinoma comprising the remainder.
  • For anal canal tumors, radiotherapy with chemotherapy yields high response and survival rates (80% and 70% respectively), with salvage surgery for treatment failures.
  • Anal margin tumors (60%) are often amenable to local excision with excellent survival (>80%).

Conclusions:

  • Treatment decisions for anal tumors depend on location and histology, with distinct optimal strategies for anal canal and anal margin disease.
  • Radiochemotherapy is the primary treatment for anal canal squamous cell carcinoma, while local excision is effective for anal margin tumors.
  • Ongoing trials aim to further refine treatment protocols and assess combined modality approaches.