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The computational restoration of autoradiographic images
1Department of Applied and Computational Mathematics, University of Sheffield, U.K.
Computers in Biology and Medicine
|January 1, 1994
Abstract:
A double integral formula is derived for the distortion in an autoradiographic image due to electron "cross-fire", and a deconvolution procedure for image restoration using a fast Fourier transform algorithm is developed. The technique is applied to a simulated autoradiograph of a uniform disc source and is found to give excellent results. Further image enhancement is obtained from the use of a spatially moving average smoothing process.