Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Analyzing the performance of diagnostic tests

J F Reed1, J J Reed

  • 1Research Department, Lehigh Valley Hospital, Allentown, PA 18105-1556.

Computer Methods and Programs in Biomedicine
|February 14, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gasoline Blow-Pipe.

International dental journal (Philadelphia, Pa.)·2023
Same author

Induced Effects on Red Imported Fire Ant (Hymenoptera: Formicidae) Forager Size Ratios by Pseudacteon spp. (Diptera: Phoridae): Implications on Bait Size Selection.

Environmental entomology·2015
Same author

Effectiveness comparison of multiple sticky-trap configurations for sampling Pseudacteon spp. phorid flies (Diptera: Phoridae).

Environmental entomology·2013
Same author

Maternal nutritional plane and selenium supply during gestation impact visceral organ mass and intestinal growth and vascularity of neonatal lamb offspring.

Journal of animal science·2013
Same author

Impacts of maternal selenium supply and nutritional plane on visceral tissues and intestinal biology in 180-day-old offspring in sheep.

Journal of animal science·2013
Same author

Effects of nutritional plane and selenium supply during gestation on visceral organ mass and indices of intestinal growth and vascularity in primiparous ewes at parturition and during early lactation.

Journal of animal science·2012
Same journal

SynTME: A tumor microenvironment-aware, pharmacology-inspired multi-stage framework for drug synergy prediction.

Computer methods and programs in biomedicine·2026
Same journal

MMFVS-Net: A triple-symmetric cross-attention network for multimodal optical image fusion and high-accuracy virtual staining of breast cancer tissues.

Computer methods and programs in biomedicine·2026
Same journal

A novel Milstein-stochastic epidemiologically-informed neural network for approaching epidemic dynamics: Application to Mpox disease.

Computer methods and programs in biomedicine·2026
Same journal

Accounting for approximation errors using surrogate-based parameter estimation of cardiac mechanics digital twins.

Computer methods and programs in biomedicine·2026
Same journal

Facial iPPG heatmap patterns based on period-aware autoencoder show association with carotid atherosclerosis towards non-contact hemodynamic assessment.

Computer methods and programs in biomedicine·2026
Same journal

Explainable machine learning models predict liver fibrosis risk and outcome in the general population: Development and multi-cohort external validation.

Computer methods and programs in biomedicine·2026
See all related articles

This study introduces a FORTRAN program for analyzing diagnostic tests. It calculates univariate and bivariate statistics to assess the combined utility of multiple tests against a gold standard.

Area of Science:

  • Medical Diagnostics
  • Biostatistics
  • Computational Biology

Background:

  • Univariate measures like sensitivity and specificity are standard for single diagnostic tests.
  • Assessing the combined utility of multiple diagnostic tests requires alternative statistical methods.

Purpose of the Study:

  • To develop and validate a computational tool for analyzing combinations of diagnostic tests.
  • To provide a method for evaluating the performance of multiple diagnostic tests simultaneously.

Main Methods:

  • A FORTRAN program was developed to compute statistical analyses.
  • The program calculates univariate statistics (sensitivity, specificity) for individual tests.
  • Bivariate concordant/discordant statistics are computed for all combinations of tests against a gold standard.

Related Experiment Videos

Main Results:

  • The program successfully computes univariate and bivariate statistics for diagnostic test combinations.
  • Analysis of all possible test combinations is feasible with the developed program.

Conclusions:

  • The FORTRAN program offers a comprehensive approach to evaluating multiple diagnostic tests.
  • This tool aids in understanding the added value of combining diagnostic tests for disease assessment.