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Updated: Aug 19, 2026

An Operant Intra-/Extra-dimensional Set-shift Task for Mice
Published on: January 22, 2016
Transfer of relational stimulus control in conditional discriminations
1Gabinette de Psicología, Oviedo, Spain.
Abstract:
Four adults were trained, using instructions and a matching-to-sample procedure, to select Stimulus B1 in the presence of Stimulus A1, B2 in the presence of A2, and B3 in the presence of A3 (the AB relations). Analogous PQ relations were trained. Afterwards, one stimulus in Set A and another stimulus in Set B appeared together as a sample, and novel Stimuli X1 and X2 were the comparisons. Responses to X1 were reinforced if the two stimuli in the sample had been related in the previous training (e.g., A1 and B1), and responses to X2 were reinforced if the two samples had not been related (e.g., A1 and B2). These were the ABX relations. In a test in which a stimulus of Set P and another of Set Q were the samples and X1 and X2 were the comparisons, 2 subjects selected X1 when the samples were P1 and Q1, P2 and Q2, and P3 and Q3, and selected X2 in the presence of the other six sample combinations (P1Q2, P1Q3, P2Q1, P2Q3, P3Q1, and P3Q2). Another subject showed the same responding after additional training. In the second experiment, 3 adults and an 11-year-old child were trained on AB, PQ, and ABX relations, and they showed the symmetrical relations BA and QP upon testing. Then all 4 of these subjects responded accurately to the PQX test. Results of Experiments 1 and 2 showed novel, consistent comparison selection based on the previously established relation between the two stimuli in the sample. In a third experiment, 3 of the subjects who had shown PQX relations were trained on EFX relations, with pairs of E and F stimuli as samples and X stimuli as comparisons. When the EF relations were tested, all 3 subjects consistently selected F1 in the presence of E1, F2 in the presence of E2, and F3 in the presence of E3 from the first trial. The results of Experiment 3 showed novel stimulus relations after training with a more complex conditional discrimination format.
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