Iron supply of Pasteurella multocida and Pasteurella haemolytica

Pasteurella multocida and Pasteurella haemolytica do not produce hydroxamate- or phenolate type siderophores. However, transport- and utilization systems could be detected for the well known siderophores ferrioxamine B, E, G, rhizoferrin and the intermediate 2,3-dihydroxybenzoic acid by means of cross-feeding tests in both Pasteurella species. Enterobactin and ferrichrome did not feed any of the Pasteurella strains tested. Additionally, alpha-ketoacids and alpha-hydroxyacids such as pyruvic acid, alpha-hydroxyisovaleric acid and others acting as primary metabolites enabled growth of P. multocida and P. haemolytica under iron limitation.