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[Levamisole in children with frequently recurring idiopathic nephrotic syndrome]
P Meregalli1, M G Bianchetti, G Imoberdorf
1Abteilung für Nephrologie, Medizinischen Universitäts-Kinderklinik Bern.
Abstract:
10 children (8 boys and 2 girls) with frequently relapsing idiopathic nephrotic syndrome were treated with levamisole (5 mg/kg weekly). In 6 children with steroid dependent nephrotic syndrome a marked reduction in steroids by 62% to 75% was possible. Severe, transient neutropenia was observed in one patient. Levamisole failed to influence the disease course positively in 3 patients with relapses associated with intercurrent illness. It is concluded that levamisole may favourably influence steroid dependence in children with frequently relapsing idiopathic nephrotic syndrome.
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