[Myocardial infarct in youth: its etiology and morphogenesis]

In the article on the grounds of 22,142 autopsy reports and 5,120 case histories retrospectively analyzed the hypothesis about the important role of chronic cumulative xenobiotic influence in the development and progress of myocardial infarction is substantiated. Spectral analysis of bones of deceased indicated significant increase of lead content in such patients. Morphological variants of coronary impairment were defined. Its morphogenesis was demonstrated to consist in formation of fibrotic, myoelastic and myofibrotic plaques and their subsequent fatty degeneration.