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Rat Model of Blood-brain Barrier Disruption to Allow Targeted Neurovascular Therapeutics
Published on: November 30, 2012
[The effect of dimephosphon on the cerebral circulatory regulation system in patients with brain tumors]
Abstract:
The paper provides the results of studies of the effects produced by the new vasoactive agent Dimephosphone, which normalizes the function of the nervous system, on the performance of the regulatory mechanisms responsible for the circulatory provision of chemical and physical homeostasis of the brain in patients with cerebral neoplasms. A five-day course of Dimephosphone monotherapy was demonstrated to normalize the cerebral circulatory regulatory system in the preoperative period. Preoperative Dimephosphone normalization of the regulatory mechanisms of cerebral circulatory provision ensures the tolerance of the cerebral circulatory system to intraoperative injury. The drug used in the course treatment of patients accelerates the normalization of cerebral vascular responsiveness at the site of surgical intervention.
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