[Is prevention of chelognathopalatoschisis possible]

The author has dealt with most frequent malformation of the visceral cranium region, cheilognathopalatoschisis. In order to be able to make precise statements on the hereditary character, he has studied 108 families with clefts, i.e. groups of kindred people in whom a cleft formation appeared in the facial area, with regard to their hereditary characteristics. While the data on the inheritance of facial clefts varied between 15 and 20%, the author was able to show that they exceed the 40% margin. The occurrence of cheilognathopalatoschisis can be almost completely prevented by selective treatment of carriers in early pregnancy.