Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Denervated skeletal muscle: MR imaging. Work in progress

M Uetani1, K Hayashi, N Matsunaga

  • 1Department of Radiology, Nagasaki University School of Medicine, Japan.

Radiology
|November 1, 1993
PubMed
Summary

Magnetic resonance (MR) imaging effectively detects changes in skeletal muscle signal intensity following denervation. This noninvasive technique shows promise for diagnosing denervation, potentially replacing electromyography.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Purification and amino-acid sequence of a nerve growth factor from the venom of Vipera russelli russelli.

Biochimica et biophysica acta·1992
Same author

Genomic structure of the human caldesmon gene.

Proceedings of the National Academy of Sciences of the United States of America·1992
Same author

Crosslinking of proteins in acetylcholine receptor-rich membranes from Torpedo californica: relation of 43-kD protein and Torpedo dystrophin to acetylcholine receptor.

Biochemistry international·1992
Same author

[The first cholera case diagnosed early in the clinical laboratory by DNA probe method].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases·1992
Same author

Transesophageal echocardiographic diagnosis of coronary sinus type atrial septal defect.

American heart journal·1992
Same author

[Phase I study of NK 622 (toremifene citrate)].

Gan to kagaku ryoho. Cancer & chemotherapy·1992

Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • Denervation of skeletal muscles can result from peripheral neuropathy or spinal radiculopathy.
  • Accurate diagnosis of denervation is crucial for patient management and treatment planning.

Purpose of the Study:

  • To assess alterations in skeletal muscle signal intensity post-denervation using magnetic resonance (MR) imaging.
  • To determine the clinical utility of MR imaging in diagnosing denervation.

Main Methods:

  • MR imaging was performed on 17 patients with denervated muscles due to peripheral neuropathy or spinal radiculopathy.
  • Analysis focused on signal intensity changes on T1-weighted and T2-weighted MR images.

Main Results:

Related Experiment Videos

  • T1-weighted images showed normal signal intensity in most denervated muscles (14/17), with high signal in three.
  • All denervated muscles exhibited high signal intensity on T2-weighted images, particularly after 15 days of paralysis.
  • Signal intensity normalized in two patients after denervation relief.

    • Conclusions:

    • MR imaging is a noninvasive and accurate tool for diagnosing skeletal muscle denervation.
    • The findings suggest MR imaging may offer an alternative to electromyography for denervation diagnosis.