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Updated: Jul 17, 2026
Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Published on: April 12, 2024
Pulmonary angiography with MR imaging: preliminary clinical experience
T M Grist1, H D Sostman, J R MacFall
1Department of Radiology, University of Wisconsin Hospitals and Clinics, Madison.
Magnetic resonance (MR) pulmonary angiography shows high sensitivity for detecting pulmonary embolism (PE). Further research is needed to improve specificity before widespread clinical adoption of this imaging technique.
Area of Science:
- Radiology
- Cardiovascular Imaging
Background:
- Pulmonary embolism (PE) is a significant clinical concern.
- Accurate diagnostic tools are crucial for timely PE detection and management.
Purpose of the Study:
- To evaluate the diagnostic accuracy of magnetic resonance (MR) pulmonary angiography for suspected pulmonary embolism.
Main Methods:
- MR pulmonary angiography was performed in 20 patients with suspected PE.
- Conventional pulmonary angiography (CPA) served as a reference standard in 14 patients.
- MR venography was integrated into the examination for 13 patients.
Main Results:
- MR pulmonary angiography demonstrated high sensitivity (92%-100%) for PE detection.
- The specificity of MR pulmonary angiography was found to be 62%.
- Simultaneous MR arteriography and venography proved feasible for identifying thrombus in both arterial and deep venous systems.
Conclusions:
- This study highlights the early clinical application of novel MR pulmonary angiography techniques.
- Enhancements in sensitivity for slow flow and increased spatial resolution are required to improve specificity.
- Further advancements are necessary to justify the routine clinical use of MR pulmonary angiography.
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