Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hardy-Weinberg Principle01:49

Hardy-Weinberg Principle

Diploid organisms have two alleles of each gene, one from each parent, in their somatic cells. Therefore, each individual contributes two alleles to the gene pool of the population. The gene pool of a population is the sum of every allele of all genes within that population and has some degree of variation. Genetic variation is typically expressed as a relative frequency, which is the percentage of the total population that has a given allele, genotype or phenotype.In the early 20th century,...
Mutation, Gene Flow, and Genetic Drift01:09

Mutation, Gene Flow, and Genetic Drift

In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).Mechanisms of Genetic VariationThe original sources of genetic variation are mutations,...
Chromosomal Theory of Inheritance01:39

Chromosomal Theory of Inheritance

In 1866, Gregor Mendel published the results of his pea plant breeding experiments, providing evidence for predictable patterns in the inheritance of physical characteristics. The significance of his findings was not immediately recognized. In fact, the existence of genes was unknown at the time. Mendel referred to hereditary units as “factors.”
Synteny and Evolution02:31

Synteny and Evolution

John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral chromosome underwent...
Stability of Equilibrium Configuration01:23

Stability of Equilibrium Configuration

Understanding the stability of equilibrium configurations is a fundamental part of mechanical engineering. In any system, there are three distinct types of equilibrium: stable, neutral, and unstable.
A stable equilibrium occurs when a system tends to return to its original position when given a small displacement, and the potential energy is at its minimum. An example of a stable equilibrium is when a cantilever beam is fixed at one end and a weight is attached to the other end. If the weight...
Stability of structures01:14

Stability of structures

In mechanical engineering, the stability of systems under various forces is critical for designing durable and efficient structures. One fundamental way to explore these concepts is by analyzing systems like two rods connected at a pivot point, O, with a torsional spring of spring constant k at the pivot point. This system is similar in appearance to a scissor jack used to change tires on a car. In this case, the arms of the linkage (equivalent to the rods in this system) are entirely vertical,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

On differentiation.

Rivista di biologia·2000
Same author

Industrial melanism revisited.

Rivista di biologia·2000
Same author

Genes and hormones may not be identified with "information".

Rivista di biologia·1999
Same author

Questions about the integrity of Darwin and macroevolution.

Rivista di biologia·1989
Same author

In vitro senescence of human keratinocyte cultures.

Cell structure and function·1987
Same author

Molecular biology: a structuralist revolution.

Rivista di biologia·1985

Related Experiment Video

Updated: Jul 20, 2026

Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin
11:17

Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin

Published on: March 10, 2021

Stability of arbitrary structures. Its implications for heredity and evolution. Part I

A Sibatani1

  • 1Wissenschaftskolleg zu Berlin.

Rivista Di Biologia
|January 1, 1993
PubMed
Summary

This study introduces reverse-reductionism, proposing that biological structures are arbitrary and can exist in multiple configurations. Evolution is seen as transformations between these configurations, guided by stable, hereditary structures.

More Related Videos

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
04:52

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

Daily Transfers, Archiving Populations, and Measuring Fitness in the Long-Term Evolution Experiment with Escherichia coli
15:00

Daily Transfers, Archiving Populations, and Measuring Fitness in the Long-Term Evolution Experiment with Escherichia coli

Published on: August 18, 2023

Related Experiment Videos

Last Updated: Jul 20, 2026

Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin
11:17

Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin

Published on: March 10, 2021

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
04:52

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

Daily Transfers, Archiving Populations, and Measuring Fitness in the Long-Term Evolution Experiment with Escherichia coli
15:00

Daily Transfers, Archiving Populations, and Measuring Fitness in the Long-Term Evolution Experiment with Escherichia coli

Published on: August 18, 2023

Area of Science:

  • Theoretical Biology
  • Philosophy of Science
  • Systems Biology

Background:

  • Traditional reductionist approaches in biology face limitations in explaining complex phenomena.
  • The concept of arbitrary structure, inspired by Saussurean linguistics, offers a new perspective.
  • Biological processes may be governed by underlying, invariant structures rather than solely by component interactions.

Purpose of the Study:

  • To propose a novel framework for understanding biological processes through "reverse-reductionism."
  • To explore the implications of arbitrary and multiple structures in biological systems.
  • To reframe the understanding of evolution as a process of configurational transformation.

Main Methods:

  • Conceptual analysis drawing parallels between linguistics and biology.
  • Axiomatic reasoning on the nature of biological structure and its configurations.
  • Theoretical modeling of hereditary structures and their dynamic maintenance across generations.

Main Results:

  • Biological structures are not unique but potentially multiple and arbitrary.
  • Structures are invariant, while their configurations are subject to transformation.
  • Hereditary structures constrain biological processes and evolution dynamically.

Conclusions:

  • Reverse-reductionism offers an alternative to reductionism for reconstructing biology.
  • Evolution involves configurational transformations within stable, hereditary structures.
  • Emergent structures predetermine potential evolutionary pathways, with materialization being contingent.