Periurethral collagen for urinary incontinence after gender reassignment surgery
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Updated: Nov 9, 2026

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
Published on: June 16, 2022
C Fitzpatrick1, S J Swierzewski, E J McGuire
1Department of Surgery, University of Michigan Medical Center, Ann Arbor.
Abstract:
We report on 2 patients, one female and one male transsexual; in both, Type III stress urinary incontinence developed after gender reassignment surgery. Both patients were treated by periurethral injection of gluteraldehyde cross-linked collagen resulting in a marked symptomatic improvement in association with a significant rise in abdominal leak point pressures. We believe these are the first reported cases of collagen injection being used for urinary incontinence after gender reassignment surgery.
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