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Updated: Aug 10, 2026
10:33
Multi-locus Variable-number Tandem-repeat Analysis of the Fish-pathogenic Bacterium Yersinia ruckeri by Multiplex PCR and Capillary Electrophoresis
Published on: June 17, 2019
[Yersinia arthritis. Long-term follow up]
1Medizinische Klinik, Kreiskrankenhaus Rendsburg, Akademisches Lehrkrankenhaus, Christian-Albrechts-Universität Kiel.
Zeitschrift Fur Rheumatologie
|July 1, 1993
Summary
Yersinia arthritis typically resolves within a year, with most patients experiencing a benign long-term prognosis. Human leukocyte antigen B27 (HLA-B27) positivity was common, but severe outcomes like ankylosing spondylitis were rare.
Area of Science:
- Rheumatology
- Infectious Diseases
- Immunology
Background:
- Yersinia arthritis is a reactive arthritis that can occur after infection with Yersinia bacteria.
- The long-term outcomes and prognostic factors for Yersinia arthritis require further elucidation.
Purpose of the Study:
- To analyze the clinical course, serological markers, and inflammatory parameters in patients with Yersinia arthritis.
- To determine the long-term prognosis and identify potential risk factors for severe disease.
Main Methods:
- A cohort of 22 patients with acute Yersinia arthritis was followed for a mean of 10.7 years.
- Clinical data, agglutinating antibody titers against Yersinia, and laboratory markers of inflammation were assessed.
- Radiological evaluation of sacroiliac joints and symphysis was performed.
Main Results:
- The acute phase of Yersinia arthritis lasted from 1 month to 1 year in most patients.
- Human leukocyte antigen B27 (HLA-B27) was positive in 73% of cases.
- One patient developed severe ankylosing spondylitis with bilateral sacroiliac joint synostosis; two others had radiological changes without clinical symptoms.
- Agglutinating antibodies and laboratory signs of inflammation were negative in all patients during the follow-up period.
Conclusions:
- Yersinia arthritis generally has a benign long-term prognosis.
- While HLA-B27 positivity is frequent, severe sequelae like ankylosing spondylitis are uncommon.
- Absence of persistent inflammation markers suggests a self-limiting process.
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