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Method for the direct specific measurement of vitamin B12 bound to transcobalamin II in plasma
S Benhayoun1, C Adjalla, J P Nicolas
1INSERM U308, Department of Biochemistry-Immunology, School of Medicine, Vandoeuvre, France.
Acta Haematologica
|January 1, 1993
Abstract:
The concentration of plasma vitamin B12 bound to transcobalamin II was measured by two methods: QUSO and Heparin Sepharose (HS). The new HS procedure provided a specific, direct measurement of vitamin B12 bound to both R binder and transcobalamin II in plasma.