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Fructose absorption

J E Riby1, T Fujisawa, N Kretchmer

  • 1Department of Nutritional Sciences, University of California at Berkeley 94720.

The American Journal of Clinical Nutrition
|November 1, 1993
PubMed
Summary
This summary is machine-generated.

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Fructose absorption in the human gut is less than previously thought. Consuming glucose alongside fructose may prevent fructose malabsorption by utilizing a shared transport system.

Area of Science:

  • Human physiology
  • Gastroenterology
  • Nutritional science

Background:

  • Fructose is a common sugar in modern diets, often consumed as sucrose or high-fructose corn syrup.
  • Understanding fructose absorption is crucial due to its prevalence and potential for malabsorption.

Purpose of the Study:

  • To determine the absorptive capacity for free fructose in the human gut.
  • To investigate the interaction between fructose and glucose absorption.

Main Methods:

  • Human gut absorption studies.
  • Analysis of monosaccharide and disaccharide transport mechanisms.

Main Results:

  • Fructose absorption capacity is significantly lower than previously estimated.

Related Experiment Videos

  • Simultaneous glucose ingestion can mitigate fructose malabsorption.
  • A shared transport system, potentially related to disaccharidases, may be involved.

    • Conclusions:

    • The human gut has a limited capacity for absorbing free fructose.
    • Co-ingestion with glucose appears to enhance fructose absorption, possibly via a sucrose-mimicking transport pathway.
    • Fructose absorption may be impaired when consumed without glucose.