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Updated: Aug 10, 2026

Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter
08:00

Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter

Published on: June 15, 2015

[First stage closure of badly tolerated ventricular septal defects in the infant]

J P Binet, J Langlois, J Bruniaux

    Archives Des Maladies Du Coeur Et Des Vaisseaux
    |June 1, 1976
    PubMed

    Insights

    One-stage closure of ventricular septal defects in infants using extracorporeal circulation and profound hypothermia yielded encouraging results. Most murmurs resolved post-surgery, with most children recovering fully, demonstrating the procedure

    Area of Science:

    • Pediatric Cardiac Surgery
    • Congenital Heart Disease
    • Surgical Innovation

    Context:

    • Ventricular septal defects (VSDs) are common congenital heart abnormalities.
    • Poorly tolerated VSDs in infants pose significant surgical challenges.
    • Current surgical approaches require careful consideration of cardiopulmonary bypass and hypothermia.

    Purpose:

    • To evaluate the efficacy and outcomes of a one-stage surgical closure for poorly tolerated VSDs in infants and small children.
    • To assess the safety and feasibility of using profound hypothermia and extracorporeal circulation in this patient population.

    Summary:

    • This study reports on the one-stage surgical closure of ventricular septal defects in infants and babies.
    • The procedure utilized extracorporeal circulation and profound hypothermia.
    • Results were encouraging, with most postoperative murmurs gradually resolving and most children achieving normal status.

    Impact:

    • Demonstrates a potentially effective surgical strategy for complex VSDs in very young patients.
    • Highlights the successful application of profound hypothermia and extracorporeal circulation in infant cardiac surgery.
    • Provides valuable data on the long-term recovery and potential neurological sequelae in this cohort.

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