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Studies on J-chain biosynthesis in tumours producing immunoglobulins in NZB mice

H Kaji

    The Biochemical Journal
    |June 15, 1976
    PubMed

    Investigation of biosynthesis of J chain in plasmacytomas induced in NZB mice revealed that this protein was not only synthesized in the cells that produce polymer immunoglobulin A but also in those that produce immunoglobulin G monomer. It was also found that protein similar to J chain of BALB/c-mice was associated with polymer immunoglobulin A but not with immunoglobulin G of NZB mouse myeloma proteins.

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