Related Experiment Video
Updated: Aug 3, 2026

07:15
Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice
Published on: March 15, 2024
Substance abuse in adolescent trauma
J M Loiselle1, M D Baker, J M Templeton
1Division of Emergency Medicine, Children's Hospital of Philadelphia, Pennsylvania.
Annals of Emergency Medicine
|October 1, 1993
Summary
A significant percentage of adolescents admitted for acute trauma test positive for alcohol or drug use. Toxicology screens are recommended for these patients, particularly those with intentional injuries.
Area of Science:
- Pediatric Emergency Medicine
- Adolescent Health
- Toxicology Screening
Background:
- Adolescent trauma is a significant public health concern.
- The prevalence of substance use in trauma patients is not well-established.
Purpose of the Study:
- To determine the prevalence of alcohol and drug use in adolescents experiencing acute trauma.
- To compare substance use rates between trauma patients and a control group.
Main Methods:
- Prospective, age-matched controlled study conducted over 20 months.
- Involved urban pediatric emergency department patients (13-19 years) admitted for trauma.
- Included an age-matched control group of asthmatic patients.
Main Results:
- 34% (22 of 65) of trauma patients tested positive for alcohol or drugs.
- Substance use was significantly higher in trauma patients compared to controls (P < .001).
- Intentional injuries showed a higher rate of positive toxicology screens (21 of 71) than unintentional injuries (1 of 63).
Conclusions:
- A substantial proportion of adolescents hospitalized for trauma have positive toxicology screens.
- Routine toxicology screening is advised for adolescents with significant trauma, especially with intentional mechanisms.
Related Concept Videos
Drug Abuse and Addiction: Pharmacological Phenomena
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Substance Use Disorders Affecting Sleep
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
Traumatic Memory
Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual remembers mundane...
Ethnic Identity within a Larger Culture
Adolescents from ethnic minority backgrounds face a multifaceted journey in forming their identities, shaped by the intersections of cultural expectations and personal exploration. For these adolescents, identity formation involves not only typical developmental challenges but also navigating the perceptions and attitudes of the majority culture. As they grow, adolescents in ethnic minority groups often become increasingly aware of stereotypes, social biases, and discrimination, all of which...
Stress and Mental Health
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
Post-traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...

