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[Late potentials and mitral valve prolapse]

J F Leclercq1, M C Malergue, P Coumel

  • 1Centre de rythmologie, hôpital Lariboisière, Paris.

Archives Des Maladies Du Coeur Et Des Vaisseaux
|March 1, 1993
PubMed
Summary
This summary is machine-generated.

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Signal-averaged electrocardiograms reveal late ventricular potentials (LP) in 38% of mitral valve prolapse (MVP) patients. Myxoid valve changes significantly increase LP prevalence, indicating potential myocardial abnormalities in MVP.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Cardiac Imaging

Context:

  • Mitral valve prolapse (MVP) is a common valvular heart condition.
  • Signal-averaged electrocardiography (SAECG) is used to detect late ventricular potentials (LP).
  • Myxoid degeneration is a characteristic feature of some MVP cases.

Purpose:

  • To investigate the prevalence of late ventricular potentials (LP) in patients with echocardiographically diagnosed mitral valve prolapse (MVP).
  • To assess the correlation between the morphological characteristics of the mitral valve in MVP and the presence of LPs.
  • To determine if LPs in MVP patients are associated with ventricular arrhythmias.

Summary:

  • Signal-averaged electrocardiograms were recorded in 100 MVP patients and 50 controls.

Related Experiment Videos

  • Late ventricular potentials (LP) were found in 38% of MVP patients versus 6% of controls (p < 0.01).
  • LP prevalence was significantly higher in MVP patients with myxoid valve changes (61%) compared to those with normal valve thickness (10.9%).
  • All six patients with severe ventricular arrhythmias had LPs.
  • LPs were more common in MVP patients with frequent ventricular extrasystoles and myxoid valve changes (70%) compared to those with normal valves (9%).

    • Impact:

    • The findings suggest a myocardial abnormality in MVP, particularly in cases with myxoid valve degeneration.
    • The presence of LPs in MVP patients may indicate an increased risk for ventricular arrhythmias.
    • SAECG could be a valuable tool for risk stratification in MVP patients.