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Published on: January 14, 2018
A new myosin I gene in Drosophila
C M Cheney1, N G Kravit, J W Verbsky
1Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110.
Abstract:
We have identified and cloned a new myosin-I cDNA, myosin 61F, from Drosophila melanogaster. The sequence of myosin 61F cDNA shows high similarity to vertebrate myosin-I sequences. Myosin 61F is most similar to bovine myosin Ib, showing 78% similarity and 63% identity. Myosin 61F is a single copy gene which maps to polytene region 61F, a genomic region with several potential myosin mutations. The identification of a myosin-I gene in Drosophila will allow genetic analysis of myosin-I function in a metazoan organism.

