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Synthesis of some 4-oxo-delta 2-thiazolin-2-ylhydrazones as potential antiprotozoal agents
A J Alves1, A C Leite, D P De Santana
1Departamento de Farmácia, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Farmaco (Societa Chimica Italiana : 1989)
|August 1, 1993
Abstract:
Several 4-oxo-delta 2-thiazolin-2-ylhydrazone derivatives 6 (6-1 - 6-19) derived from the cyclization reaction between the thiosemicarbazones 5 and homologous alpha-chloroacids were prepared. Only compound 6-2 was found to be active against Entamoeba histolytica and Trichomonas vaginalis.