Related Experiment Video
Updated: Aug 9, 2026

12:12
Methods to Assess Beta Cell Death Mediated by Cytotoxic T Lymphocytes
Published on: June 16, 2011
Cytotoxic activity of human lymphocyte plasma membranes
Clinical and Experimental Immunology
|August 1, 1976
Abstract:
Plasma membrane fractions isolated from normal human peripheral blood lymphocytes have considerable cytolytic activity towards a cultured human lymphoblast cell line and mouse mastocytoma cells. Other subcellular fractions, including lysosomes, have low cytolytic activity. It is suggested that this cytotoxic potential in lymphocyte plasma membranes is normally latent but can be activated by prolonged and intimate contact with target cell plasma membranes.

