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Related Experiment Videos

Borderline hypertension. A 24-hour abnormality

A Bergbrant1, L Hansson, S Jern

  • 1Department of Medicine, Ostra Hospital, University of Göteborg, Sweden.

American Journal of Hypertension
|August 1, 1993
PubMed
Summary
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Borderline hypertension (BH) is a real condition, not an artifact. Ambulatory blood pressure monitoring shows elevated nighttime blood pressure in BH individuals compared to normotensive controls.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Clinical Physiology

Background:

  • Borderline hypertension (BH) diagnosis is debated, with questions about whether it reflects true elevated blood pressure or psychological factors.
  • Understanding basal blood pressure levels, especially during sleep, is crucial for accurately defining BH.

Purpose of the Study:

  • To investigate if borderline hypertension (BH) is a distinct physiological state.
  • To compare ambulatory blood pressure (ABP) in subjects with BH versus normotensive controls (NC).
  • To determine if BH subjects exhibit elevated blood pressure during sleep or periods of low arousal.

Main Methods:

  • Twenty-four-hour ambulatory blood pressure (ABP) monitoring using the Spacelabs 90202 device.
  • Recruitment of 49 BH subjects (SBP 140–160 mmHg or DBP 85–95 mmHg) and 18 NC (SBP 110–130 mmHg, DBP 60–80 mmHg) from an unbiased population (age 20–28).

Related Experiment Videos

  • Confirmation of BH and NC classifications using intra-arterial blood pressure recordings.

    • Main Results:

    • Systolic blood pressure (SBP) was significantly higher in the BH group compared to the NC group over the entire 24-hour period and during all four 6-hour intervals (morning, afternoon, evening, night).
    • Diastolic blood pressure (DBP) showed a smaller but significant difference between groups in the afternoon and evening, but not in the morning or at night.
    • Blood pressure followed expected diurnal variations, with highest values in the afternoon and lowest at night in both groups.

    Conclusions:

    • The findings support borderline hypertension (BH) as a genuine physiological condition.
    • Elevated 24-hour systolic blood pressure, including nighttime levels, characterizes individuals with BH.
    • Ambulatory blood pressure monitoring is essential for differentiating BH from normotensive states.