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Ionomer-based bone substitute in otologic surgery

G Geyer1, J Helms

  • 1ENT Department, University of Würzburg, Germany.

European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
|January 1, 1993
PubMed
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This study shows that the self-curing bone substitute, Ionocem, effectively bonds with bone in reconstructive otologic surgery. It demonstrated high success rates for middle ear prostheses and mastoid cavity obliteration.

Area of Science:

  • Biomaterials Science
  • Otolaryngology
  • Regenerative Medicine

Background:

  • Self-curing bone substitutes offer potential advantages in reconstructive surgery.
  • Ionocem is an ionomer-based cement designed for bone regeneration and fixation.
  • Previous applications in otologic surgery require evaluation of its efficacy and safety.

Purpose of the Study:

  • To evaluate the clinical performance of Ionocem as a bone substitute in various otologic surgical procedures.
  • To assess the success rates and complications associated with Ionocem use in middle ear prostheses, mastoid obliteration, and canal wall reconstruction.

Main Methods:

  • Retrospective analysis of 945 alloplastic middle ear prostheses using Ionos ossicle.
  • Implantation of granular Ionogran in 46 ears for mastoid cavity obliteration.

Related Experiment Videos

  • Posterior canal wall reconstruction in 74 patients using the self-curing bone substitute.

    • Main Results:

    • A 94% take-rate was observed for middle ear prostheses, with 50% of revisions due to dislocation.
    • Complete mucosal overgrowth was achieved within 3 months for mastoid obliteration.
    • Canal wall reconstruction required revisions in 12 cases due to epithelial deficits or retraction.

    Conclusions:

    • Ionomer-based cement (Ionocem) is a viable bone substitute in reconstructive otologic surgery.
    • While effective, prosthesis dislocation and epithelial integrity are areas for continued monitoring and improvement.
    • Ionocem demonstrates utility in middle ear reconstruction, mastoid obliteration, and canal wall reconstruction.