Related Experiment Video
Updated: Aug 24, 2026

Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
Published on: September 16, 2011
[Study on basophil releasability induced by anti-IgE in allergic rhinitis]
1Central Hospital, Shengli Petroleum Administration, Dongying, Shandong.
Abstract:
We have investigated the basophil releasability induced by anti-IgE in allergic rhinitis patients and normal subjects by reverse human basophil degranulation tests. The results showed that anti-IgE-mediated basophil releasability and total serum IgE were significantly higher in allergic rhinitis patients than that in normal subjects. However, anti-IgE-mediated basophil releasability, total serum IgE and blood eosinophil count were not closely correlated with each other.
Related Concept Videos
Antibody Structure
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Allergic Reactions
Allergic Drug Reactions

