[Clinicopathological analysis of midline peripheral T-cell lymphoma]

Sixty-one cases of midline peripheral T-cell lymphoma (MPTL) are reported. All were proven by immunohistochemical staining: UCHL-1 (pan-T cell marker) was positive in 93.4%, L26 (pan-B cell marker) MAC 387 and Lyso were all negative. MPTL were more frequently seen in the nasal cavity than in the palate and larynx, the ratio of male to female was 3.62:1, mean age 38.6 years. According to morpho-logical characteristics, two types could be distinguished: monomorphic (14 cases) and polymorphic (47 cases), with different 5-year survival rates. Those with small-medium ALC and convoluted nuclei had a better prognosis.