Related Experiment Videos
Nucleotide and deduced amino acid sequence of human ribosomal protein L18
M Puder1, G F Barnard, R J Staniunas
1Division of Cellular and Molecular Biology, Dana-Farber Cancer Institute Harvard Medical School, Boston, MA.
Biochimica Et Biophysica Acta
|October 19, 1993
Abstract:
Ribosomal protein L18 mRNA is overexpressed in human colorectal cancer compared to normal colon tissue. We report the nucleotide sequence of human L18 cDNA derived from a normal colon source. There were no mutational changes in segments of L18 cDNA derived from two tumor sources. The L18 cDNA was 690 base pairs long and predicts a single open reading frame of 564 nucleotides, encoding 188 amino acids with a M(r) = 21,621, it is homologous to rat L18 and Xenopus laevis L14.