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[Intestinal parasitosis: physiopathologic aspects]
1Médico Gastroenterólogo del Hospital Nacional Edgardo Rebagliati Martins, Instituto Peruano de Seguridad Social, Lima, Perú.
Summary
Intestinal parasites cause diverse pathological changes affecting digestive function. Host response to parasite aggression, influenced by virulence and infestation phase, dictates clinical manifestations.
Area of Science:
- Parasitology
- Gastroenterology
- Pathophysiology
Context:
- Parasitic infections present a wide spectrum of pathological changes.
- Recent advancements have improved understanding of parasite products' direct impact on digestive function.
- Both adult and migratory forms of intestinal parasites exert significant pathogenetic effects.
Purpose:
- To provide a concise review of the physiopathologic effects of intestinal parasite infestations.
- To highlight the mechanisms by which parasites disrupt host physiology.
- To underscore the importance of understanding parasite-host interactions in disease.
Summary:
- Intestinal parasites induce diverse pathological changes, impacting digestive function through direct actions and released products.
- Pathogenesis involves both luminal/mucosal adult forms and migratory larval/adult stages.
- Clinical manifestations are closely linked to the host's immune response to parasitic aggression, varying with infestation phase and parasite virulence.
Impact:
- Enhances understanding of parasitic disease mechanisms.
- Provides a foundation for developing targeted therapeutic strategies.
- Contributes to the knowledge base for clinical diagnosis and management of intestinal parasitic infections.