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[Intestinal parasitosis: physiopathologic aspects]

O Frisancho Velarde1

  • 1Médico Gastroenterólogo del Hospital Nacional Edgardo Rebagliati Martins, Instituto Peruano de Seguridad Social, Lima, Perú.

Revista De Gastroenterologia Del Peru : Organo Oficial De La Sociedad De Gastroenterologia Del Peru
|January 1, 1993
PubMed
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Intestinal parasites cause diverse pathological changes affecting digestive function. Host response to parasite aggression, influenced by virulence and infestation phase, dictates clinical manifestations.

Area of Science:

  • Parasitology
  • Gastroenterology
  • Pathophysiology

Context:

  • Parasitic infections present a wide spectrum of pathological changes.
  • Recent advancements have improved understanding of parasite products' direct impact on digestive function.
  • Both adult and migratory forms of intestinal parasites exert significant pathogenetic effects.

Purpose:

  • To provide a concise review of the physiopathologic effects of intestinal parasite infestations.
  • To highlight the mechanisms by which parasites disrupt host physiology.
  • To underscore the importance of understanding parasite-host interactions in disease.

Summary:

  • Intestinal parasites induce diverse pathological changes, impacting digestive function through direct actions and released products.

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  • Pathogenesis involves both luminal/mucosal adult forms and migratory larval/adult stages.
  • Clinical manifestations are closely linked to the host's immune response to parasitic aggression, varying with infestation phase and parasite virulence.

    • Impact:

    • Enhances understanding of parasitic disease mechanisms.
    • Provides a foundation for developing targeted therapeutic strategies.
    • Contributes to the knowledge base for clinical diagnosis and management of intestinal parasitic infections.