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Lithium-induced parathyroid dysfunction: a case report and review of the literature
1University of Mississippi, Jackson 39216.
The Annals of Pharmacotherapy
|September 1, 1993
Abstract
Objective:
Twenty-six cases of lithium-induced hyperparathyroidism have been reported in the literature. This article describes an additional case that illustrates current management recommendations.
Design:
Case report. Clinical presentation and proposed mechanisms of the suspected drug-induced effect are discussed.
Conclusions:
Serum calcium concentrations should be determined before and periodically during long-term lithium carbonate therapy. Discontinuation of therapy in patients who develop lithium-induced parathyroid dysfunction generally corrects calcium and parathyroid hormone concentrations. Surgery is indicated in patients with complications of hyperparathyroidism.