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The isolation and nucleotide sequence of the pyruvate decarboxylase gene from Kluyveromyces marxianus
1Department of Microbiology, University of Guelph, Ontario, Canada.
Current Genetics
|September 1, 1993
Abstract:
We have determined the nucleotide sequence of a 2360-basepair (bp) region of the Kluyveromyces marxianus genome containing the structural gene for the enzyme pyruvate decarboxylase (PDC). Comparison of the deduced amino-acid sequence of this gene to that of the Saccharomyces cerevisiae PDC genes reveals extensive homology including a motif common to thiamin diphosphate-dependent enzymes.